Tamoxifen won't work on hormone-receptor-negative breast cancer. Tamoxifen is available in two forms: a pill taken once a day (brand name: Nolvadex) or a liquid form (brand name: Soltamox). If you dislike pills or you're having trouble swallowing tamoxifen pills, Soltamox can help make it easier to stay on your treatment plan. Most doctors recommend taking tamoxifen at the same time each day. — while you are taking tamoxifen and for 2 months afterward. You should not take tamoxifen if you are breastfeeding, pregnant, trying to get pregnant, or if there is any chance that you could be pregnant. You should use an effective non-hormonal type of birth control — such as condoms, a diaphragm along with spermicide, or a non-hormonal I. Ask your doctor which type of non-hormonal birth control would be best for you. Since its approval in 1998, tamoxifen has been used to treat millions of women and men diagnosed with hormone-receptor-positive breast cancer. While an aromatase inhibitor is the first hormonal therapy medicine choice for postmenopausal women, tamoxifen is the first choice for premenopausal women and is still a good choice for postmenopausal women who can't take an aromatase inhibitor. : Tamoxifen is an antiestrogen with proven efficacy and low toxicity in the treatment of breast cancer. However, tamoxifen has been shown to exert a number of nonhor-monalas well as hormonal effects. One nonhormonal effect of tamoxifen is the induction of transforming growth factor-β (TGF-β) secretion. TGF-β has been implicated in the pathogenesis of radiation-induced fibrosis. : Data from 196 women were included in the analysis. Eighty-four women were postmeno-pausal patients who participated in a randomized trial testing tamoxifen as an adjuvant to postmastectomy radiotherapy. The radiotherapy technique employed an 8-MV photon field covering the axillary and the infraclavicular and supraclavicular regions of the affected side of the chest; the chest wall was treated with an abutted electron field.
Tamoxifen Nolvadex is a medication used to treat hormone-receptor positive early and metastatic breast cancers and to reduce breast cancer risk in undiagnosed women at higher-than-average risk of developing breast cancer. Learn more about tamoxifen. Verapamil VPL and/or tamoxifen TAM combined with chemotherapy in the treatment of refractory lung cancer. Liu XY, Fang H, Fang J. Tumor Clinical College.