Metronidazole is an antibiotic that is used to treat a wide variety of infections. It works by stopping the growth of certain bacteria and parasites. This antibiotic treats only certain bacterial and parasitic infections. It will not work for viral infections (such as common cold, flu). Using any antibiotic when it is not needed can cause it to not work for future infections. Metronidazole may also be used with other medications to treat certain stomach/intestinal ulcers caused by a bacteria (H. Take this medication by mouth as directed by your doctor. To prevent stomach upset, take this medication with food or a full glass of water or milk. | Which infections should metronidazole be used for? | First line indications for metronidazole | Second line indications for metronidazole | Issues associated with metronidazole Metronidazole is a core antibiotic for the treatment of anaerobic infections. Its mechanism of action is not entirely clear, but it is thought that the active metabolite interferes with DNA synthesis. Anaerobic infections are usually treated empirically, without susceptibility testing. Studies carried out in New Zealand have shown that anaerobic bacteria are still mostly susceptible to metronidazole and it remains a good empirical choice for suspected anaerobic infections. Metronidazole 400 mg, twice daily, for seven days OR a single dose of metronidazole 2 g (5 x 400 mg tablets) Bacterial vaginosis results from the replacement of normal vaginal flora by anaerobic bacteria such as Gardnerella, Bacteroides and Mobilunculus species. A seven day course of metronidazole is now favoured as it is more effective than the single dose regimen for resolving symptoms, although compliance may be an issue. One study found that symptoms had resolved in 62% of women three to four weeks after the single-dose course and in 82% after the seven day course.
Metronidazole Flagyl is used for treating bacterial infections of the skin, vagina, stomach, joints, or respiratory tract. Synergistic effects between amoxicillin, metronidazole, and the hydroxymetabolite of metronidazole against Actinobacillus actinomycetemcomitans.