Medications known as serotonin reuptake inhibitors (SRIs) have been used for many years to treat OCD. An SRI known as Anafranil has been available the longest and is the best-studied medicine for OCD. Anafranil has been approved by the FDA to treat OCD in adults and children 10 years of age and above. Although it has been shown to be very effective, it has been associated with some potentially harmful side effects. This has led clinicians to recommend another class of antidepressant medications, the serotonin reuptake inhibitors (SSRIs), as the first line of medication treatment. SSRIs directly affect serotonin, a neurotransmitter, or chemical messenger, in the brain. There is growing evidence that SSRIs are as effective as Anafranil in treating OCD, with fewer side effects. Obsessive-compulsive disorder (OCD) is a type of anxiety disorder that involves reoccurring obsessive thoughts and compulsive behaviors performed in response to these thoughts. OCD can be quite an inhibiting disorder for many people, making it incredibly difficult for them to go about their daily life. OCD is typically treated with a psychotherapy and medication, and often people find that a combination of the two approaches is the most effective. Antidepressants are usually the first type of medication used to treat obsessive-compulsive disorder. The Food and Drug Administration has approved clomipramine (Anafranil), fluoxetine (Prozac), fluvoxamine (Luvox), paroxetine (Paxil, Pexeva), and sertraline (Zoloft) to treat OCD. Clomipramine (Anafranil) is a type of medication known as a tricyclic antidepressant. It has been approved by the FDA to treat OCD in adults and children ages ten and older.
Up to 50% of patients with OCD have failed to respond in SSRI trials, so looking for. Surveying duloxetine augmentation in treatment of resistant OCD. Duloxetine, due to its serotonin norepinephrine reuptake inhibition profile, may be worth investigating in OCD patients. To our knowledge only case reports have.