Prednisone is a potent corticosteroid drug used to treat inflammatory forms of arthritis as well as some types of cancer and autoimmune disease. It's available in tablet and liquid formulations and functions as an immunosuppressant, tempering inflammation by blunting the immune response. Inflammation is the body's natural response to anything it considers harmful. When the immune system identifies a harmful agent, it releases chemicals into the bloodstream which cause tissues to swell, in part to increase the size of blood vessels and allow larger immune cells closer access to the site of an injury or infection. With certain autoimmune disorders, the immune response is abnormal and excessive. Such is the case with rheumatoid arthritis (RA), a condition where the immune system mistakenly attacks healthy joints. Acute RA symptoms often flares without notice, causing increased pain, swelling, and injury to the affected joint. Knee swelling is a sign that there’s a problem within the knee. It can be the body’s response to damage to a part of the knee, an overuse injury, or a symptom of an underlying disease or condition. Knee swelling happens when fluid collects in or around the joint of a knee. Another term for a swollen knee is knee effusion or water on the knee. If knee swelling persists for more than three days, if swelling worsens, or if you experience severe pain alongside the swelling, seek the advice of a medical professional. In the meantime, here are eight ways to treat knee swelling quickly at home. Avoid sports and other weight-bearing activities for 24 hours or more to give your knee a break and a chance to heal. However, it’s still good to gently straighten the knee and flex it multiple times a day.
You don't say if you are taking any other meds or how long you have been taking the prednisone which would make it easier to give you a proper answer. The down sides include puffy appearance, severe insomnia, very severe leg pain usually from the knee down, steroid psychosis and bone density issues from longer term use . But yes the swelling, legpain/weakness are serious side effects that the prednisone can cause and you should contact your doctor immediately. Its normally used in short term use but in longer use cases most general practitioners miss treat and miss diagnose the side effects . Unfortunately, with this being Good Friday that could be difficult so if you can't contact your doctor then I would contact your pharmacy if possible and see what they advise. Its a very dangerous medication to stop without tapering . If that doesn't work then maybe stop taking the prednisone and see what happens. Our family has bin completely turned upside down by this medication . If things get worse then get medical help and go to emergency if necessary. I'm a nurse, prednisone is not a medicine that can ever just be stopped, it must be Weaned/tapered. I've also personally been on high dose prednisone and can vouch for the bone and muscle aches, insomnia, palpitations, "moonface", etc. Talk to your doctor if your side effects are worse than the condition the medicine is treating. My daughter has bone density issues in her spine and massive pain related to its use in her auto immune disease . It's an evil medication, with to few benefits . Most the time, unfortunately, it's necessary to push through. What ever anyone does DO NOT STOP TAKING THIS MEDICATION WITHOUT TAPERING IT . I am taking 50 MG of prednisone for about 3 weeks now. Feels like someone is hitting my knees with a hammer. Took two Aleve and didn’t do anything after an hour. Yoy are suppose to contact your Doctor before doing this. I would definately report it to someone in your practice and see if they could prescribe something else, ASAP. There are only a few benefits to the use of it, immune suppression, and clear skin . In contrast to anabolic steroids (used by “bodybuilders”), corticosteroids are used in inflammatory conditions for their anti–inflammatory effects. They have a rapid onset of action, and profoundly affect many parts of the immune system as well as most other body systems. Corticosteroids are a cornerstone of treating most types of vasculitis, and are often used in combination with other immunosuppressive medications. Many of the side–effects of steroids are predictable. All are related to: 1) the amount of steroid a patient takes in his/her daily dose, and 2) the length of time the patient remains on the medication. We emphasize that not all side–effects occur in all patients. Despite the numerous potential side–effects of corticosteroids listed below, their introduction into patient care 50 years ago revolutionized the treatment of many diseases, including vasculitis.
Prednisolone and prednisone are man-made glucocorticoids, which are used to. They have a strong anti-inflammatory effect and reduce the swelling and pain in. and joint damage; simple pain relieving medicines such as paracetamol. Swollen knee — Comprehensive overview covers symptoms, causes. your doctor might suggest an oral corticosteroid, such as prednisone.